Organic Carbamates in Drug Design and Medicinal Chemistry
نویسندگان
چکیده
منابع مشابه
Organic Carbamates in Drug Design and Medicinal Chemistry
The carbamate group is a key structural motif in many approved drugs and prodrugs. There is an increasing use of carbamates in medicinal chemistry and many derivatives are specifically designed to make drug-target interactions through their carbamate moiety. In this Perspective, we present properties and stabilities of carbamates, reagents and chemical methodologies for the synthesis of carbama...
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Organic carbamates are the stable class of compounds derived from the unstable carbamic acid having O-CO-NHlinkage [1,2] with unique applications in the field of pharmaceuticals, agrochemicals (pesticides, herbicides, insecticides, fungicides etc.), intermediates in organic synthesis, in the forms of drugs and prodrugs, for the protection of amino groups in peptide chemistry, as a useful syntho...
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ژورنال
عنوان ژورنال: Journal of Medicinal Chemistry
سال: 2015
ISSN: 0022-2623,1520-4804
DOI: 10.1021/jm501371s